2zvw: Difference between revisions

<table><tr><td colspan='2'>[[2zvw]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZVW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZVW FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zvv|2zvv]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zvw OCA], [http://pdbe.org/2zvw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zvw RCSB], [http://www.ebi.ac.uk/pdbsum/2zvw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zvw ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PCNA2_ARATH PCNA2_ARATH]] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity). May be involved in UV resistance.<ref>PMID:18494853</ref> [[http://www.uniprot.org/uniprot/CDN1A_HUMAN CDN1A_HUMAN]] May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.<ref>PMID:8242751</ref> <ref>PMID:9106657</ref> 

[[Category: Arath]]

[[Category: Morikawa, K]]

[[Category: Oyama, T]]

[[Category: Strzalka, W]]

[[Category: Tori, K]]

[[Category: Protein-peptide complex]]