7jk2: Difference between revisions
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==Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1)== | |||
<StructureSection load='7jk2' size='340' side='right'caption='[[7jk2]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7jk2]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JK2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JK2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jk2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jk2 OCA], [https://pdbe.org/7jk2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jk2 RCSB], [https://www.ebi.ac.uk/pdbsum/7jk2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jk2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ORC2_DROME ORC2_DROME] Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.<ref>PMID:11137005</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Bleichert F]] | |||
[[Category: Schmidt JM]] | |||
Latest revision as of 14:52, 6 March 2024
Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1)
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