7jlu: Difference between revisions
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==Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ== | |||
<StructureSection load='7jlu' size='340' side='right'caption='[[7jlu]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7jlu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_benthamiana Nicotiana benthamiana] and [https://en.wikipedia.org/wiki/Xanthomonas_euvesicatoria Xanthomonas euvesicatoria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JLU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jlu OCA], [https://pdbe.org/7jlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jlu RCSB], [https://www.ebi.ac.uk/pdbsum/7jlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jlu ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ROQ1_NICBE ROQ1_NICBE] Disease resistance (R) protein that specifically recognizes the Xanthomonas and Pseudomonas effector proteins XopQ and HopQ1, and triggers cell death (PubMed:28891100). Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).<ref>PMID:28891100</ref> <ref>PMID:31439792</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Nicotiana benthamiana]] | |||
[[Category: Xanthomonas euvesicatoria]] | |||
[[Category: King M]] | |||
[[Category: Lui F]] | |||
[[Category: Martin R]] | |||
[[Category: Nogales E]] | |||
[[Category: Qi T]] | |||
[[Category: Staskawicz BJ]] | |||
[[Category: Toth C]] | |||
[[Category: Zhang H]] | |||
Latest revision as of 14:52, 6 March 2024
Structure of the activated Roq1 resistosome directly recognizing the pathogen effector XopQ
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