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==Crystal structure of human Brachyury G177D variant in complex with Afatinib==
==Crystal structure of human Brachyury G177D variant in complex with Afatinib==
<StructureSection load='6zu8' size='340' side='right'caption='[[6zu8]]' scene=''>
<StructureSection load='6zu8' size='340' side='right'caption='[[6zu8]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZU8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6ZU8 FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZU8 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6zu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zu8 OCA], [http://pdbe.org/6zu8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6zu8 RCSB], [http://www.ebi.ac.uk/pdbsum/6zu8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6zu8 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0WN:N-{4-[(3-CHLORO-4-FLUOROPHENYL)AMINO]-7-[(3S)-TETRAHYDROFURAN-3-YLOXY]QUINAZOLIN-6-YL}-4-(DIMETHYLAMINO)BUTANAMIDE'>0WN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zu8 OCA], [https://pdbe.org/6zu8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zu8 RCSB], [https://www.ebi.ac.uk/pdbsum/6zu8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zu8 ProSAT]</span></td></tr>
</table>
</table>
==See Also==
*[[Brachyury|Brachyury]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 09:19, 9 October 2024

Crystal structure of human Brachyury G177D variant in complex with Afatinib

6zu8, resolution 1.95Å

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