5l7s: Difference between revisions

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<StructureSection load='5l7s' size='340' side='right'caption='[[5l7s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='5l7s' size='340' side='right'caption='[[5l7s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5l7s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Botrytis_infestans Botrytis infestans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L7S OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5L7S FirstGlance]. <br>
<table><tr><td colspan='2'>[[5l7s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phytophthora_infestans Phytophthora infestans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L7S FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PITG_09316 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4787 Botrytis infestans])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5l7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l7s OCA], [http://pdbe.org/5l7s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l7s RCSB], [http://www.ebi.ac.uk/pdbsum/5l7s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l7s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l7s OCA], [https://pdbe.org/5l7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l7s RCSB], [https://www.ebi.ac.uk/pdbsum/5l7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l7s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RD54_PHYIT RD54_PHYIT] Effector that specifically binds host autophagy protein ATG8CL of the ATG8 family to stimulate autophagosome formation and subsequent autophagy rather than blocking autophagic flux (PubMed:26765567, PubMed:29932422). The pathogen remodels host-microbe interface by co-opting the host autophagy machinery which plays a key role in plant immunity (PubMed:29932422). PexRD54 competes with the autophagy cargo receptor Joka2 to deplete it out of ATG8CL complexes and interferes with Joka2's positive effect on pathogen defense (PubMed:26765567, PubMed:29932422).<ref>PMID:26765567</ref> <ref>PMID:29932422</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Botrytis infestans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Banfield, M J]]
[[Category: Phytophthora infestans]]
[[Category: Hughes, R K]]
[[Category: Banfield MJ]]
[[Category: Maqbool, A]]
[[Category: Hughes RK]]
[[Category: Phytophthora infestan]]
[[Category: Maqbool A]]
[[Category: Rxlr effector]]
[[Category: Signaling protein]]
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