3c78: Difference between revisions

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<StructureSection load='3c78' size='340' side='right'caption='[[3c78]], [[Resolution|resolution]] 0.98&Aring;' scene=''>
<StructureSection load='3c78' size='340' side='right'caption='[[3c78]], [[Resolution|resolution]] 0.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3c78]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhopr Rhopr]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2at7 2at7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C78 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3C78 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3c78]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C78 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDD:FE(III)+2,4-DIMETHYL+DEUTEROPORPHYRIN+IX'>FDD</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.98&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2at8|2at8]], [[3c77|3c77]], [[1x8p|1x8p]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FDD:FE(III)+2,4-DIMETHYL+DEUTEROPORPHYRIN+IX'>FDD</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3c78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c78 OCA], [http://pdbe.org/3c78 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c78 RCSB], [http://www.ebi.ac.uk/pdbsum/3c78 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c78 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c78 OCA], [https://pdbe.org/3c78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c78 RCSB], [https://www.ebi.ac.uk/pdbsum/3c78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c78 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).  
[https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/3c78_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/3c78_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rhopr]]
[[Category: Rhodnius prolixus]]
[[Category: Amoia, A M]]
[[Category: Amoia AM]]
[[Category: Montfort, W R]]
[[Category: Montfort WR]]
[[Category: Dimethyl deuteroporphyrin ix]]
[[Category: Beta barrel]]
[[Category: Ferric]]
[[Category: Heme analog]]
[[Category: Iron]]
[[Category: Lipocalin]]
[[Category: Metal-binding]]
[[Category: Secreted]]
[[Category: Transport protein]]
[[Category: Vasoactive]]
[[Category: Vasodilator]]
Retrieved from "https://proteopedia.org/3c78"