7cq7: Difference between revisions
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New page: '''Unreleased structure''' The entry 7cq7 is ON HOLD Authors: Yang, G.H., Lu, Y.M., Zhang, Y.M., Jia, Y.T., Li, X.M., Lei, J.L. Description: Structure of the human CLCN7-OSTM1 complex ... |
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The entry | ==Structure of the human CLCN7-OSTM1 complex with ADP== | ||
<StructureSection load='7cq7' size='340' side='right'caption='[[7cq7]], [[Resolution|resolution]] 3.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7cq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CQ7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [https://pdbe.org/7cq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Infantile osteopetrosis with neuroaxonal dysplasia. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Required for osteoclast and melanocyte maturation and function.<ref>PMID:21527911</ref> | |||
==See Also== | |||
*[[Ion channels 3D structures|Ion channels 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Yang | [[Category: Jia YT]] | ||
[[Category: | [[Category: Lei JL]] | ||
[[Category: Li XM]] | |||
[[Category: Lu YM]] | |||
[[Category: Yang GH]] | |||
[[Category: Zhang YM]] | |||