7cq7: Difference between revisions

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New page: '''Unreleased structure''' The entry 7cq7 is ON HOLD Authors: Yang, G.H., Lu, Y.M., Zhang, Y.M., Jia, Y.T., Li, X.M., Lei, J.L. Description: Structure of the human CLCN7-OSTM1 complex ...
 
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'''Unreleased structure'''


The entry 7cq7 is ON HOLD
==Structure of the human CLCN7-OSTM1 complex with ADP==
<StructureSection load='7cq7' size='340' side='right'caption='[[7cq7]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7cq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CQ7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [https://pdbe.org/7cq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Infantile osteopetrosis with neuroaxonal dysplasia. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Required for osteoclast and melanocyte maturation and function.<ref>PMID:21527911</ref>


Authors: Yang, G.H., Lu, Y.M., Zhang, Y.M., Jia, Y.T., Li, X.M., Lei, J.L.
==See Also==
 
*[[Ion channels 3D structures|Ion channels 3D structures]]
Description: Structure of the human CLCN7-OSTM1 complex with ADP
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Lei, J.L]]
__TOC__
[[Category: Jia, Y.T]]
</StructureSection>
[[Category: Lu, Y.M]]
[[Category: Homo sapiens]]
[[Category: Zhang, Y.M]]
[[Category: Large Structures]]
[[Category: Yang, G.H]]
[[Category: Jia YT]]
[[Category: Li, X.M]]
[[Category: Lei JL]]
[[Category: Li XM]]
[[Category: Lu YM]]
[[Category: Yang GH]]
[[Category: Zhang YM]]