7a2f: Difference between revisions

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New page: '''Unreleased structure''' The entry 7a2f is ON HOLD until Paper Publication Authors: Singh, A.K., Blaazer, A.R., Zara, L., de Esch, I.J.P., Leurs, R., Brown, D.G. Description: Crystal...
 
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'''Unreleased structure'''


The entry 7a2f is ON HOLD  until Paper Publication
==Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656==
<StructureSection load='7a2f' size='340' side='right'caption='[[7a2f]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7a2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A2F FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=QWZ:1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl)ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one'>QWZ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a2f OCA], [https://pdbe.org/7a2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a2f RCSB], [https://www.ebi.ac.uk/pdbsum/7a2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a2f ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8WQX9_9TRYP Q8WQX9_9TRYP]


Authors: Singh, A.K., Blaazer, A.R., Zara, L., de Esch, I.J.P., Leurs, R., Brown, D.G.
==See Also==
 
*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
Description: Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Leurs, R]]
[[Category: Large Structures]]
[[Category: Singh, A.K]]
[[Category: Trypanosoma brucei]]
[[Category: Brown, D.G]]
[[Category: Blaazer AR]]
[[Category: De Esch, I.J.P]]
[[Category: Brown DG]]
[[Category: Zara, L]]
[[Category: Leurs R]]
[[Category: Blaazer, A.R]]
[[Category: Singh AK]]
[[Category: Zara L]]
[[Category: De Esch IJP]]