5n8c: Difference between revisions
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<StructureSection load='5n8c' size='340' side='right'caption='[[5n8c]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5n8c' size='340' side='right'caption='[[5n8c]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5n8c]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5n8c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N8C FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8Q8:(2~{S})-3-AZANYL-2-[[(1~{R})-5-[2-[4-[[2-(HYDROXYMETHYL)IMIDAZOL-1-YL]METHYL]PHENYL]ETHYNYL]-2,3-DIHYDRO-1~{H}-INDEN-1-YL]AMINO]-3-METHYL-~{N}-OXIDANYL-BUTANAMIDE'>8Q8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8Q8:(2~{S})-3-AZANYL-2-[[(1~{R})-5-[2-[4-[[2-(HYDROXYMETHYL)IMIDAZOL-1-YL]METHYL]PHENYL]ETHYNYL]-2,3-DIHYDRO-1~{H}-INDEN-1-YL]AMINO]-3-METHYL-~{N}-OXIDANYL-BUTANAMIDE'>8Q8</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n8c OCA], [https://pdbe.org/5n8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n8c RCSB], [https://www.ebi.ac.uk/pdbsum/5n8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n8c ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 28: | Line 27: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Andersen | [[Category: Andersen OA]] | ||
[[Category: Barker | [[Category: Barker J]] | ||
[[Category: Brooks | [[Category: Brooks M]] | ||
[[Category: Cheng | [[Category: Cheng RK]] | ||
[[Category: Cross | [[Category: Cross JB]] | ||
[[Category: Kwong | [[Category: Kwong J]] | ||
[[Category: Ryan | [[Category: Ryan MD]] | ||
[[Category: Wood | [[Category: Wood M]] | ||
[[Category: Zhang | [[Category: Zhang J]] | ||
Latest revision as of 12:34, 15 November 2023
Crystal structure of Pseudomonas aeruginosa LpxC complexed with inhibitor
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