7cvp: Difference between revisions
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The entry | ==The Crystal Structure of human PHGDH from Biortus.== | ||
<StructureSection load='7cvp' size='340' side='right'caption='[[7cvp]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7cvp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CVP FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvp OCA], [https://pdbe.org/7cvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cvp RCSB], [https://www.ebi.ac.uk/pdbsum/7cvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvp ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:[https://omim.org/entry/601815 601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SERA_HUMAN SERA_HUMAN] | |||
==See Also== | |||
*[[Phosphoglycerate dehydrogenase|Phosphoglycerate dehydrogenase]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Cheng W]] | ||
[[Category: | [[Category: Huang Y]] | ||
[[Category: | [[Category: Lin D]] | ||
[[Category: | [[Category: Lv Z]] | ||
[[Category: Miao Q]] | |||
[[Category: Wang F]] | |||
Latest revision as of 16:17, 29 November 2023
The Crystal Structure of human PHGDH from Biortus.
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