7cwe: Difference between revisions
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New page: '''Unreleased structure''' The entry 7cwe is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Human Fructose-1,6-bisphosphatase 1 in APO R-state== | |||
<StructureSection load='7cwe' size='340' side='right'caption='[[7cwe]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7cwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CWE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cwe OCA], [https://pdbe.org/7cwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cwe RCSB], [https://www.ebi.ac.uk/pdbsum/7cwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cwe ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:[https://omim.org/entry/229700 229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.<ref>PMID:9382095</ref> <ref>PMID:12126934</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] | |||
==See Also== | |||
*[[Fructose-1%2C6-bisphosphatase 3D structures|Fructose-1%2C6-bisphosphatase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cao Y]] | |||
[[Category: Chen Y]] | |||
[[Category: Li C]] | |||
[[Category: Zhang J]] | |||
Latest revision as of 16:17, 29 November 2023
Human Fructose-1,6-bisphosphatase 1 in APO R-state
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