7jx7: Difference between revisions
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New page: '''Unreleased structure''' The entry 7jx7 is ON HOLD Authors: Patel, K., Low, J.K.K., Mackay, J.P., Solomon, P.D. Description: BRD2-BD2 in complex with a diacetylated-H2A.Z peptide [[C... |
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==BRD2-BD2 in complex with a diacetylated-H2A.Z peptide== | |||
<StructureSection load='7jx7' size='340' side='right'caption='[[7jx7]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7jx7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JX7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jx7 OCA], [https://pdbe.org/7jx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jx7 RCSB], [https://www.ebi.ac.uk/pdbsum/7jx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jx7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> | |||
==See Also== | |||
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: Mackay | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Synthetic construct]] | |||
[[Category: Low JKK]] | |||
[[Category: Mackay JP]] | |||
[[Category: Patel K]] | |||
[[Category: Solomon PD]] | |||
Latest revision as of 13:38, 6 November 2024
BRD2-BD2 in complex with a diacetylated-H2A.Z peptide
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