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'''Unreleased structure'''


The entry 7jxg is ON HOLD
==Structural model for Fe-containing human acireductone dioxygenase==
<StructureSection load='7jxg' size='340' side='right'caption='[[7jxg]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7jxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JXG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jxg OCA], [https://pdbe.org/7jxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jxg RCSB], [https://www.ebi.ac.uk/pdbsum/7jxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jxg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MTND_HUMAN MTND_HUMAN] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.[HAMAP-Rule:MF_03154]<ref>PMID:11602742</ref> <ref>PMID:15938715</ref>


Authors: Pochapsky, T.C., Liu, X., Deshpande, A., Ringe, D., Garber, A., Ryan, J.
==See Also==
 
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
Description: Structural model for Fe-containing human acireductone dioxygenase
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Garber, A]]
__TOC__
[[Category: Ringe, D]]
</StructureSection>
[[Category: Pochapsky, T.C]]
[[Category: Homo sapiens]]
[[Category: Liu, X]]
[[Category: Large Structures]]
[[Category: Deshpande, A]]
[[Category: Deshpande A]]
[[Category: Ryan, J]]
[[Category: Garber A]]
[[Category: Liu X]]
[[Category: Pochapsky TC]]
[[Category: Ringe D]]
[[Category: Ryan J]]
Retrieved from "https://proteopedia.org/7jxg"