5x3l: Difference between revisions
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==Solution structure of a novel antimicrobial peptide, P1, from jumper ant Myrmecia pilosula== | ==Solution structure of a novel antimicrobial peptide, P1, from jumper ant Myrmecia pilosula== | ||
<StructureSection load='5x3l' size='340' side='right'caption='[[5x3l | <StructureSection load='5x3l' size='340' side='right'caption='[[5x3l]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5x3l]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X3L OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5x3l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myrmecia_pilosula Myrmecia pilosula]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X3L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X3L FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x3l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x3l OCA], [https://pdbe.org/5x3l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x3l RCSB], [https://www.ebi.ac.uk/pdbsum/5x3l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x3l ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TX1AB_MYRPI TX1AB_MYRPI] Has strong cytotoxic and hemolytic activities. Is more potent against mononuclear leukocytes than against granulocytes. The synthesized peptide 57-76 shows a potent and broad spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, and also against the fungus C.albicans. Adopts an alpha-helical structure.<ref>PMID:15639237</ref> <ref>PMID:9701394</ref> <ref>PMID:9813247</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 13: | Line 13: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Myrmecia pilosula]] | ||
[[Category: | [[Category: Chen C]] | ||
[[Category: | [[Category: Tseng T-S]] | ||