Protein G: Difference between revisions

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<StructureSection load='1uwx' size='340' side='right' caption='Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code [[1uwx]]).' scene=''>
<StructureSection load='1uwx' size='340' side='right' caption='Protein G domain II (grey) complex with mouse Fab heavy chain (red) and light chain (aqua) (PDB code [[1uwx]]).' scene=''>
'''Protein G''' (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins<ref>PMID:3131664</ref>.  
'''Protein G''' or '''immunoglobulin-binding protein G''' (ProG) is a cell surface protein from Streptococcal bacteria which binds Fab and Fc regions of immunoglobulins<ref>PMID:3131664</ref>.  


For ProG  immunoglobulin-binding domain see [[Chameleon peptide]].
For ProG  immunoglobulin-binding domain see [[Chameleon peptide]].
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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*Streptococcus Protein G residues 2-68
*Streptococcus Protein G domain I or GBI residues 2-68


**[[6u8c]] – StProG + antibody – ''Streptococcus''<br />
**[[3gb1]] – StProG domain B1 – Streptococcus - NMR<br />
**[[8ug0]], [[8ug2]] – StProG domain B1 (mutant)<br />
**[[6hka]] – StProG domain B1/ATM peptide<br />
**[[6hpj]] – StProG domain B1/ASF-1 + RNA - NMR<br />
**[[6u8c]] – StProG + antibody<br />


*Streptococcus Protein G residues 56-118
*Streptococcus Protein G residues 56-118
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**[[1em7]] – StProG (mutant) <br />
**[[1em7]] – StProG (mutant) <br />


*Streptococcus Protein G B1 domain residues 228-282
*Streptococcus Protein G residues 228-282


**[[1pga]], [[1pgb]], [[2ju6]], [[2rmm]], [[2rpv]], [[1mpe]], [[1q10]], [[2j52]], [[2j53]], [[2k0p]], [[3mp9]], [[1gb1]] - StProG  <br />
**[[1mpe]], [[1pga]], [[1pgb]], [[1q10]], [[2ju6]], [[2rmm]], [[2rpv]], [[2j52]], [[2j53]], [[2k0p]] - StProG  <br />
**[[2gb1]], [[3gb1]], [[5ub0]] - StProG - NMR <br />
**[[1mvk]] – StProG (mutant) <br />
**[[1mvk]], [[1fcl]], [[1fd6]], [[1em7]], [[3v3x]] – StProG (mutant) <br />
**[[7qtr]], [[7qts]] - StProG - NMR<br />
**[[1q10]] – StProG (mutant) – NMR<br />
**[[1mvk]] – StProG (mutant) - NMR<br />
**[[1mi0]], [[1mhx]] – ProG (mutant) ''Finegoldia magna''<br />
**[[5jxv]] – StProG/ubiquitin-like protein - NMR<br />
**[[2den]] – StProG/ubiquitin-like protein + ubiquitin - NMR<br />
**[[9cht]] – StProG/p53 + E3A + protein E6 Cryo EM<br />


*Streptococcus Protein G albumin-binding domain residues 254-299
*Streptococcus Protein G residues 254-299


**[[1gjs]], [[1gjt]] - StProG albumin-binding domain - NMR<br />
**[[1gjs]], [[1gjt]] - StProG albumin-binding domain - NMR<br />


*Streptococcus Protein G 3rd Igg-binding domain residues 300-357
*Streptococcus Protein G residues 300-357


**[[3fil]], [[1pgx]], [[2igd]], [[1igd]] - StProG <br />
**[[1igd]], [[1pgx]], [[2igd]], [[3fil]] - StProG <br />
**[[3v3x]], [[5bmg]] – StProG (mutant) <br />
**[[3v3x]], [[6c9o]], [[6nl6]], [[6nl7]], [[6nl8]], [[6nl9]], [[6nlb]], [[7da8]], [[9i2i]], [[9t8z]], [[12lo]] – StProG (mutant) <br />
**[[2plp]] - StProG - NMR<br />
**[[2plp]], [[8um7]], [[8um9]], [[8uma]], [[8umb]], [[8ums]] - StProG - NMR<br />
**[[2jsv]], [[2kq4]], [[2kwd]], [[1fcl]], [[1fd6]] - StProG (mutant) - NMR<br />
**[[1fcl]], [[1fd6]], [[2jsv]], [[2kq4]], [[2kwd]] - StProG (mutant) - NMR<br />
**[[1igc]] – StProG + Igg1 Fab<br />
**[[1igc]] – StProG domain III + Igg1 Fab<br />
**[[9rxk]] – StProG + Pit2<br />
**[[3ui3]] – StProG/VAPD <br />
**[[2kn4]] – StProG domain B1/splicing factor - NMR<br />
**[[9g4t]] – StProG/CSOSCA – Cryo EM <br />
**[[6v9i]] – StProG/cullin-5 + RBX2 – Cryo EM <br />
**[[2khu]], [[2mbb]] – StProG/DNA polymerase iota <br />
**[[2khw]] – StProG/DNA polymerase iota + ubiquitin<br />
**[[5lde]] – StProG/VFLIP <br />


*Streptococcus Protein G domains II+III residues 367-430
*Streptococcus Protein G residues 328-384


**[[2on8]], [[2igg]] - StProG <br />
**[[9kl7]], [[9kls]], [[9klt]], [[9klu]] - StProG (mutant)<br />
**[[2igh]] StProG – NMR<br />
 
*Streptococcus Protein G residues 367-430
 
**[[2on8]] - StProG <br />
**[[2onq]] – StProG (mutant) <br />
**[[2onq]] – StProG (mutant) <br />
**[[1gb4]] – StProG (mutant) – NMR<br />
**[[1gb4]], [[6njf]] – StProG (mutant) – NMR<br />
**[[1fcc]] – StProG + Igg1 Fc<br />
**[[1fcc]] – StProG + Igg1 Fc<br />


*Streptococcus Protein G residues 443-497
*Streptococcus Protein G domain III or GB3 residues 443-497


**[[8wcj]] - StProG (mutant)<br />
**[[1p7e]], [[1p7f]], [[2lum]] - StProG - NMR<br />
**[[1p7e]], [[1p7f]], [[2lum]] - StProG - NMR<br />
**[[1zxh]] - StProG (mutant) - NMR<br />
**[[1zxh]] - StProG (mutant) - NMR<br />
**[[8tfr]] - StProG + antibody<br />
**[[6uyg]] - StProG + envelope glycoprotein + antibody<br />
**[[6w00]] - StProG + peptide + antibody<br />


*Protein G  
*Protein G  
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**[[2gi9]], [[2qmt]] – SaProG domain B1 (mutant) – Staphylococcus aureus<br />
**[[2gi9]], [[2qmt]] – SaProG domain B1 (mutant) – Staphylococcus aureus<br />
**[[2klk]] - SaProG immunoglobulin-binding domain - NMR<br />
**[[2klk]] - SaProG immunoglobulin-binding domain - NMR<br />
**[[9fa8]] - EcProG antibody-binding domain C2 1-65 – Escherichia coli - NMR<br />
**[[9a9t]], [[9a9u]] - EcProG antibody-binding domain C2 1-65 (mutant) – NMR<br />
**[[8r40]] - ProG immunoglobulin-binding domain III 201-281+ diabody – Rabies virus<br />


}}
}}
[[Category:Topic Page]]
== References ==
== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]