6ut6: Difference between revisions

Line 1:

====

==Cryo-EM structure of the Escherichia coli McrBC complex==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance].

<table><tr><td colspan='2'>[[6ut6]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UT6 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6UT6 FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ut6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ut6 OCA], [~~http~~://pdbe.org/6ut6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ut6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ut6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ut6 ProSAT]</td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.28Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6ut6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ut6 OCA], [https://pdbe.org/6ut6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ut6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ut6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ut6 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/MCRB_ECOLI MCRB_ECOLI] Recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad range of DNA methylases and appears to act against 5-methylcytosine preceded by a purine residue. Binds to DNA containing methylated cytosines; also binds to GTP. Isoform 33 kDa is less active than isoform 51 kDa and may play a role in regulating the activity of isoform 51 kDa by competing with it in DNA and protein binding abilities.

__TOC__

</StructureSection>

[[Category: Escherichia coli K-12]]

[[Category: Large Structures]]

[[Category: ~~Z-disk~~]]

[[Category: Chappie JS]]

[[Category: Hosford CJ]]

[[Category: Niu Y]]

[[Category: Suzuki H]]

[[Category: Walz T]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-====
+==Cryo-EM structure of the Escherichia coli McrBC complex==
-<StructureSection load='6ut6' size='340' side='right'caption='[[6ut6]]' scene=''>
+<StructureSection load='6ut6' size='340' side='right'caption='[[6ut6]], [[Resolution|resolution]] 3.28&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ut6]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UT6 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ut6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ut6 OCA], [http://pdbe.org/6ut6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ut6 RCSB], [http://www.ebi.ac.uk/pdbsum/6ut6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ut6 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.28&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ut6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ut6 OCA], [https://pdbe.org/6ut6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ut6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ut6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ut6 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/MCRB_ECOLI MCRB_ECOLI] Recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad range of DNA methylases and appears to act against 5-methylcytosine preceded by a purine residue. Binds to DNA containing methylated cytosines; also binds to GTP. Isoform 33 kDa is less active than isoform 51 kDa and may play a role in regulating the activity of isoform 51 kDa by competing with it in DNA and protein binding abilities.
 __TOC__
 </StructureSection>
+[[Category: Escherichia coli K-12]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Chappie JS]]
+[[Category: Hosford CJ]]
+[[Category: Niu Y]]
+[[Category: Suzuki H]]
+[[Category: Walz T]]