Fascin: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
FASC 3D structure shows it to contain <scene name='86/862889/Cv/2'>4 β-trefoil domains</scene>. A complex between FASC and an anti-metastatic agent shows the inhibitor binding to domains 1 and 2 <ref>PMID:30773430</ref>. | FASC 3D structure shows it to contain <scene name='86/862889/Cv/2'>4 β-trefoil domains</scene>. A complex between FASC and an anti-metastatic agent shows the <scene name='86/862889/Cv/3'>inhibitor binding to domains 1 and 2</scene> <ref>PMID:30773430</ref>. <scene name='86/862889/Cv/4'>The anti-metastatic agent is situated in deep pocket</scene>. | ||
</StructureSection> | </StructureSection> | ||
== 3D structures of fascin == | == 3D structures of fascin == | ||
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[[6i0z]], [[6i17]], [[6i16]], [[6i18]], [[6i11]], [[6i10]], [[6i13]], [[6i12]], [[6i15]], [[6i14]] - hFASC + anti-metastatic inhibitor<br /> | [[6i0z]], [[6i17]], [[6i16]], [[6i18]], [[6i11]], [[6i10]], [[6i13]], [[6i12]], [[6i15]], [[6i14]] - hFASC + anti-metastatic inhibitor<br /> | ||
[[6b0t]] - hFASC + inhibitor<br /> | [[6b0t]] - hFASC + inhibitor<br /> | ||
[[8vo6]], [[8vo7]], [[8vo8]], [[8vo9]], [[8voa]] – hFASC + actin – Cryo EM<br /> | |||
[[7zau]] – hFASC + nanobody<br /> | |||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
