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New page: left|200px<br /> <applet load="1u8k" size="450" color="white" frame="true" align="right" spinBox="true" caption="1u8k, resolution 2.24Å" /> '''Crystal structure o...
 
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[[Image:1u8k.gif|left|200px]]<br />
<applet load="1u8k" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1u8k, resolution 2.24&Aring;" />
'''Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LELDKWASL'''<br />


==About this Structure==
==Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LELDKWASL==
1U8K is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1U8K OCA].  
<StructureSection load='1u8k' size='340' side='right'caption='[[1u8k]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1u8k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U8K FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u8k OCA], [https://pdbe.org/1u8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u8k RCSB], [https://www.ebi.ac.uk/pdbsum/1u8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u8k ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u8/1u8k_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u8k ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of human antibody|3D structures of human antibody]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Bryson, S.]]
[[Category: Large Structures]]
[[Category: Cunningham, A.]]
[[Category: Bryson S]]
[[Category: Dong, A.]]
[[Category: Julien J-P]]
[[Category: Hynes, R.C.]]
[[Category: Pai EF]]
[[Category: Julien, J.P.]]
[[Category: Katinger, H.]]
[[Category: Klein, M.]]
[[Category: Kunert, R.]]
[[Category: Pai, E.F.]]
[[Category: fab complex]]
[[Category: gp41 peptide]]
[[Category: hiv-1 neutralization]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Thu Nov  8 14:32:45 2007''
Retrieved from "https://proteopedia.org/1u8k"