7klj: Difference between revisions
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New page: '''Unreleased structure''' The entry 7klj is ON HOLD Authors: Zeng, H., Dong, A., Loppnau, P., Hutchinson, A., Seitova, A., Edwards, A.M., Arrowsmith, C.H., Halabelian, L., Structural G... |
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The entry | ==Crystal structure of the WD-repeat domain of human KIF21A== | ||
<StructureSection load='7klj' size='340' side='right'caption='[[7klj]], [[Resolution|resolution]] 1.52Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7klj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KLJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7klj OCA], [https://pdbe.org/7klj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7klj RCSB], [https://www.ebi.ac.uk/pdbsum/7klj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7klj ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/KI21A_HUMAN KI21A_HUMAN] Congenital fibrosis of extraocular muscles. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KI21A_HUMAN KI21A_HUMAN] Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity (By similarity). | |||
==See Also== | |||
*[[Kinesin 3D Structures|Kinesin 3D Structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Dong A]] | ||
[[Category: | [[Category: Edwards AM]] | ||
[[Category: | [[Category: Halabelian L]] | ||
[[Category: Loppnau | [[Category: Hutchinson A]] | ||
[[Category: | [[Category: Loppnau P]] | ||
[[Category: | [[Category: Seitova A]] | ||
[[Category: Zeng H]] | |||