7cq7: Difference between revisions

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====

==Structure of the human CLCN7-OSTM1 complex with ADP==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance].

<table><tr><td colspan='2'>[[7cq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CQ7 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7CQ7 FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [~~http~~://pdbe.org/7cq7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [https://pdbe.org/7cq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</td></tr>

</table>

== Disease ==

[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Infantile osteopetrosis with neuroaxonal dysplasia. The disease is caused by variants affecting the gene represented in this entry.

== Function ==

[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Required for osteoclast and melanocyte maturation and function.<ref>PMID:21527911</ref>

==See Also==

*[[Ion channels 3D structures|Ion channels 3D structures]]

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: ~~Z-disk~~]]

[[Category: Jia YT]]

[[Category: Lei JL]]

[[Category: Li XM]]

[[Category: Lu YM]]

[[Category: Yang GH]]

[[Category: Zhang YM]]

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-====
+==Structure of the human CLCN7-OSTM1 complex with ADP==
-<StructureSection load='7cq7' size='340' side='right'caption='[[7cq7]]' scene=''>
+<StructureSection load='7cq7' size='340' side='right'caption='[[7cq7]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7cq7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CQ7 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [http://pdbe.org/7cq7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [http://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cq7 OCA], [https://pdbe.org/7cq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7cq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cq7 ProSAT]</span></td></tr>
 </table>
+== Disease ==
+[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Infantile osteopetrosis with neuroaxonal dysplasia. The disease is caused by variants affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/OSTM1_HUMAN OSTM1_HUMAN] Required for osteoclast and melanocyte maturation and function.<ref>PMID:21527911</ref>
+==See Also==
+*[[Ion channels 3D structures|Ion channels 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Jia YT]]
+[[Category: Lei JL]]
+[[Category: Li XM]]
+[[Category: Lu YM]]
+[[Category: Yang GH]]
+[[Category: Zhang YM]]