7ayb: Difference between revisions
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==Crystal Structure of wild type human mitochondrial 2-Enoyl Thioester Reductase (MECR)== | |||
<StructureSection load='7ayb' size='340' side='right'caption='[[7ayb]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7ayb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AYB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ayb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ayb OCA], [https://pdbe.org/7ayb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ayb RCSB], [https://www.ebi.ac.uk/pdbsum/7ayb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ayb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MECR_HUMAN MECR_HUMAN] Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. | |||
==See Also== | |||
*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Autio KJ]] | ||
[[Category: | [[Category: Hiltunen JK]] | ||
[[Category: | [[Category: Kastaniotis AJ]] | ||
[[Category: | [[Category: Koski MK]] | ||
[[Category: Rahman MT]] | |||
[[Category: Wierenga RK]] | |||
Latest revision as of 07:51, 7 February 2024
Crystal Structure of wild type human mitochondrial 2-Enoyl Thioester Reductase (MECR)
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