7k72: Difference between revisions
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New page: ==Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD== <StructureSection load='7k72' size='340' side='right'caption='7k72' scene=''> == Structural highlights == <t... |
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==Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD== | ==Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD== | ||
<StructureSection load='7k72' size='340' side='right'caption='[[7k72]]' scene=''> | <StructureSection load='7k72' size='340' side='right'caption='[[7k72]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K72 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[7k72]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K72 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k72 OCA], [https://pdbe.org/7k72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k72 RCSB], [https://www.ebi.ac.uk/pdbsum/7k72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k72 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DNLJ_MYCTU DNLJ_MYCTU] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588] | |||
==See Also== | |||
*[[DNA ligase 3D structures|DNA ligase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
Latest revision as of 15:18, 18 October 2023
Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD
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