1ni2: Difference between revisions

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<StructureSection load='1ni2' size='340' side='right'caption='[[1ni2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1ni2' size='340' side='right'caption='[[1ni2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ni2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NI2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1NI2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ni2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NI2 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VIL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ni2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ni2 OCA], [http://pdbe.org/1ni2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ni2 RCSB], [http://www.ebi.ac.uk/pdbsum/1ni2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ni2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ni2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ni2 OCA], [https://pdbe.org/1ni2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ni2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ni2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ni2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref>
[https://www.uniprot.org/uniprot/EZRI_HUMAN EZRI_HUMAN] Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<ref>PMID:17881735</ref> <ref>PMID:18270268</ref> <ref>PMID:19111582</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bretscher, A P]]
[[Category: Bretscher AP]]
[[Category: Cerione, R A]]
[[Category: Cerione RA]]
[[Category: Karplus, P A]]
[[Category: Karplus PA]]
[[Category: Nassar, N]]
[[Category: Nassar N]]
[[Category: Smith, W J]]
[[Category: Smith WJ]]
[[Category: Acyl-coa-like domain]]
[[Category: Ferm]]
[[Category: Keystone]]
[[Category: Ph/ptb-like domain]]
[[Category: Structural protein]]
[[Category: Ubiquitin-like domain]]
Retrieved from "https://proteopedia.org/1ni2"