7b2r: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
New page: '''Unreleased structure''' The entry 7b2r is ON HOLD Authors: Chaikuad, A., Knapp, S., Structural Genomics Consortium (SGC) Description: Crystal structure of NHL domain of TRIM2 [[Cate...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 7b2r is ON HOLD
==Crystal structure of NHL domain of TRIM2==
 
<StructureSection load='7b2r' size='340' side='right'caption='[[7b2r]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
Authors: Chaikuad, A., Knapp, S., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7b2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B2R FirstGlance]. <br>
Description: Crystal structure of NHL domain of TRIM2
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
[[Category: Chaikuad, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b2r OCA], [https://pdbe.org/7b2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b2r RCSB], [https://www.ebi.ac.uk/pdbsum/7b2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b2r ProSAT]</span></td></tr>
[[Category: Knapp, S]]
</table>
[[Category: Structural Genomics Consortium (Sgc)]]
== Disease ==
[https://www.uniprot.org/uniprot/TRIM2_HUMAN TRIM2_HUMAN] Charcot-Marie-Tooth disease type 2R. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TRIM2_HUMAN TRIM2_HUMAN] UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance.[UniProtKB:Q9ESN6]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chaikuad A]]
[[Category: Knapp S]]
Retrieved from "https://proteopedia.org/7b2r"