1p1t: Difference between revisions

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==NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit==
==NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit==
<StructureSection load='1p1t' size='340' side='right'caption='[[1p1t]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1p1t' size='340' side='right'caption='[[1p1t]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1p1t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1T OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1P1T FirstGlance]. <br>
<table><tr><td colspan='2'>[[1p1t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P1T FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSTF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1p1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1t OCA], [http://pdbe.org/1p1t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1p1t RCSB], [http://www.ebi.ac.uk/pdbsum/1p1t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1p1t ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p1t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1t OCA], [https://pdbe.org/1p1t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p1t RCSB], [https://www.ebi.ac.uk/pdbsum/1p1t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p1t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CSTF2_HUMAN CSTF2_HUMAN]] One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).<ref>PMID:9199325</ref>
[https://www.uniprot.org/uniprot/CSTF2_HUMAN CSTF2_HUMAN] One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).<ref>PMID:9199325</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Perez-Canadillas, J M]]
[[Category: Perez-Canadillas JM]]
[[Category: Varani, G]]
[[Category: Varani G]]
[[Category: C-terminal helix]]
[[Category: N-terminal helix]]
[[Category: Rna binding protein]]
[[Category: Rna recognition motif]]