7dpa: Difference between revisions
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New page: '''Unreleased structure''' The entry 7dpa is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex== | |||
<StructureSection load='7dpa' size='340' side='right'caption='[[7dpa]], [[Resolution|resolution]] 3.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7dpa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DPA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dpa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dpa OCA], [https://pdbe.org/7dpa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dpa RCSB], [https://www.ebi.ac.uk/pdbsum/7dpa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dpa ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DOCK5_HUMAN DOCK5_HUMAN] Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).[UniProtKB:B2RY04]<ref>PMID:19004829</ref> | |||
==See Also== | |||
*[[Dedicator of cytokinesis protein 3D structures|Dedicator of cytokinesis protein 3D structures]] | |||
*[[Rac 3D structures|Rac 3D structures]] | |||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ehara H]] | |||
[[Category: Hanada K]] | |||
[[Category: Ikeda M]] | |||
[[Category: Katsura K]] | |||
[[Category: Kaushik R]] | |||
[[Category: Kukimoto-Niino M]] | |||
[[Category: Mishima-Tsumagari C]] | |||
[[Category: Shirouzu M]] | |||
[[Category: Uchikubo-Kamo T]] | |||
[[Category: Yokoyama T]] | |||
[[Category: Yonemochi M]] | |||
[[Category: Zhang KYJ]] | |||
Latest revision as of 10:53, 27 March 2024
Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex
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