1sz2: Difference between revisions

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<StructureSection load='1sz2' size='340' side='right'caption='[[1sz2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1sz2' size='340' side='right'caption='[[1sz2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sz2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1SZ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sz2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZ2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1q18|1q18]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sz2 OCA], [https://pdbe.org/1sz2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sz2 RCSB], [https://www.ebi.ac.uk/pdbsum/1sz2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sz2 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLK, B2388, Z3654, ECS3268 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1sz2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sz2 OCA], [http://pdbe.org/1sz2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sz2 RCSB], [http://www.ebi.ac.uk/pdbsum/1sz2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1sz2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLK_ECOLI GLK_ECOLI]] Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.  
[https://www.uniprot.org/uniprot/GLK_ECO57 GLK_ECO57] Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1sz2_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1sz2_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Glucokinase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cygler, M]]
[[Category: Cygler M]]
[[Category: Iannuzzi, P]]
[[Category: Iannuzzi P]]
[[Category: Li, Y]]
[[Category: Li Y]]
[[Category: Lunin, V V]]
[[Category: Lunin VV]]
[[Category: Matte, A]]
[[Category: Matte A]]
[[Category: Schrag, J D]]
[[Category: Schrag JD]]
[[Category: Atp-dependent]]
[[Category: Glucose binding]]
[[Category: Transferase]]