1thz: Difference between revisions

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<StructureSection load='1thz' size='340' side='right'caption='[[1thz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='1thz' size='340' side='right'caption='[[1thz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1thz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1THZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1thz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1THZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1THZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=326:2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC+ACID'>326</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1g8m|1g8m]], [[1m9n|1m9n]], [[1oz0|1oz0]], [[1pkx|1pkx]], [[1p4r|1p4r]], [[1pl0|1pl0]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=326:2-{(E)-[5-HYDROXY-3-METHYL-1-(2-METHYL-4-SULFOPHENYL)-1H-PYRAZOL-4-YL]DIAZENYL}-4-SULFOBENZOIC+ACID'>326</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATIC, PURH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1thz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1thz OCA], [https://pdbe.org/1thz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1thz RCSB], [https://www.ebi.ac.uk/pdbsum/1thz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1thz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1thz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1thz OCA], [http://pdbe.org/1thz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1thz RCSB], [http://www.ebi.ac.uk/pdbsum/1thz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1thz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PUR9_CHICK PUR9_CHICK]] Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.<ref>PMID:12501179</ref>
[https://www.uniprot.org/uniprot/PUR9_CHICK PUR9_CHICK] Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.<ref>PMID:12501179</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Li, C]]
[[Category: Li C]]
[[Category: Olson, A J]]
[[Category: Olson AJ]]
[[Category: Wilson, I A]]
[[Category: Wilson IA]]
[[Category: Xu, L]]
[[Category: Xu L]]
[[Category: Atic]]
[[Category: Cancer target]]
[[Category: Hydrolase]]
[[Category: Purine biosynthesis]]
[[Category: Transferase]]
[[Category: Virtual ligand screening]]
Retrieved from "https://proteopedia.org/1thz"