1tl6: Difference between revisions
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==Solution structure of T4 bacteriphage AsiA monomer== | ==Solution structure of T4 bacteriphage AsiA monomer== | ||
<StructureSection load='1tl6' size='340' side='right'caption='[[1tl6 | <StructureSection load='1tl6' size='340' side='right'caption='[[1tl6]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1tl6]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1tl6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TL6 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tl6 OCA], [https://pdbe.org/1tl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tl6 RCSB], [https://www.ebi.ac.uk/pdbsum/1tl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tl6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ASIA_BPT4 ASIA_BPT4] Transcriptional inhibitor. Inhibits sigma 70-directed transcription by weakening its interaction with the core of the host's RNA polymerase. This allows Gp55 to successfully compete for the core enzyme. Plays an important role during the prereplicative period of phage T4 development.<ref>PMID:8021178</ref> <ref>PMID:15257291</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia virus T4]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Demeler | [[Category: Demeler B]] | ||
[[Category: Lambert | [[Category: Lambert LJ]] | ||
[[Category: Schirf | [[Category: Schirf V]] | ||
[[Category: Wei | [[Category: Wei Y]] | ||
[[Category: Werner | [[Category: Werner MH]] | ||