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==Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)==
==Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)==
<StructureSection load='1ugk' size='340' side='right'caption='[[1ugk]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1ugk' size='340' side='right'caption='[[1ugk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ugk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1UGK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ugk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UGK FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kazusa cDNA fj00418 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ugk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugk OCA], [http://pdbe.org/1ugk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ugk RCSB], [http://www.ebi.ac.uk/pdbsum/1ugk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ugk ProSAT], [http://www.topsan.org/Proteins/RSGI/1ugk TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ugk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugk OCA], [https://pdbe.org/1ugk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ugk RCSB], [https://www.ebi.ac.uk/pdbsum/1ugk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ugk ProSAT], [https://www.topsan.org/Proteins/RSGI/1ugk TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SYT4_HUMAN SYT4_HUMAN]] May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.  
[https://www.uniprot.org/uniprot/SYT4_HUMAN SYT4_HUMAN] May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Aoki, M]]
[[Category: Aoki M]]
[[Category: Hayashi, F]]
[[Category: Hayashi F]]
[[Category: Hirota, H]]
[[Category: Hirota H]]
[[Category: Inoue, M]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Kikuno, R]]
[[Category: Kikuno R]]
[[Category: Matsuda, T]]
[[Category: Matsuda T]]
[[Category: Matsuo, Y]]
[[Category: Matsuo Y]]
[[Category: Nagase, T]]
[[Category: Nagase T]]
[[Category: Nagashima, T]]
[[Category: Nagashima T]]
[[Category: Nakayama, M]]
[[Category: Nakayama M]]
[[Category: Ohara, O]]
[[Category: Ohara O]]
[[Category: Osanai, T]]
[[Category: Osanai T]]
[[Category: Structural genomic]]
[[Category: Seki E]]
[[Category: Seki, E]]
[[Category: Shirouzu M]]
[[Category: Shirouzu, M]]
[[Category: Tanaka A]]
[[Category: Tanaka, A]]
[[Category: Terada T]]
[[Category: Terada, T]]
[[Category: Yabuki T]]
[[Category: Yabuki, T]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Yoshida M]]
[[Category: Yoshida, M]]
[[Category: Beta sandwich]]
[[Category: Protein binding]]
[[Category: Rsgi]]
Retrieved from "https://proteopedia.org/1ugk"