7l8m: Difference between revisions

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'''Unreleased structure'''


The entry 7l8m is ON HOLD
==Crystal structure of human GPX4-U46C mutant K48L==
<StructureSection load='7l8m' size='340' side='right'caption='[[7l8m]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7l8m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7L8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7L8M FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.07&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7l8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7l8m OCA], [https://pdbe.org/7l8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7l8m RCSB], [https://www.ebi.ac.uk/pdbsum/7l8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7l8m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GPX4_HUMAN GPX4_HUMAN] Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity).


Authors:  
==See Also==
 
*[[Glutathione peroxidase|Glutathione peroxidase]]
Description:  
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Conrad M]]
[[Category: Forouhar F]]
[[Category: Friedman J]]
[[Category: Liu H]]
[[Category: Ramesh S]]
[[Category: Saneto R]]
[[Category: Seibt T]]
[[Category: Shchepinov MS]]
[[Category: Stockwell BR]]
[[Category: Xia X]]
Retrieved from "https://proteopedia.org/7l8m"