1xe4: Difference between revisions

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<StructureSection load='1xe4' size='340' side='right'caption='[[1xe4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='1xe4' size='340' side='right'caption='[[1xe4]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xe4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12706 Atcc 12706]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XE4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XE4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xe4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Weissella_viridescens Weissella viridescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XE4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ne9|1ne9]], [[1p4n|1p4n]], [[1lrz|1lrz]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">femx ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1629 ATCC 12706])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xe4 OCA], [https://pdbe.org/1xe4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xe4 RCSB], [https://www.ebi.ac.uk/pdbsum/1xe4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xe4 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoylpentapeptide-lysine_N(6)-alanyltransferase UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.10 2.3.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xe4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xe4 OCA], [http://pdbe.org/1xe4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xe4 RCSB], [http://www.ebi.ac.uk/pdbsum/1xe4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xe4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FEMX_WEIVI FEMX_WEIVI] Involved in the synthesis of the bacterial cell wall. Catalyzes the addition of alanine into the interchain peptide bridge of peptidoglycan precursor using aminoacyl-tRNA(Ala) as amino acid donor. This alanine is added to the epsilon-amino group of the L-lysine of the peptidoglycan UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine, in a ribosome-independent mechanism (PubMed:11083873, PubMed:4248527, PubMed:12679335, PubMed:15901708, PubMed:23744707). Specific for UDP-N-acetyl-muramoyl-pentapeptide. Has no activity toward UDP-N-acetyl-muramoyl-tetrapeptide or UDP-N-acetyl-muramoyl-tripeptide (PubMed:15901708). Also acts on L-seryl-tRNA(Ser) (PubMed:4248527).<ref>PMID:11083873</ref> <ref>PMID:12679335</ref> <ref>PMID:15901708</ref> <ref>PMID:23744707</ref> <ref>PMID:4248527</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 12706]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arthur, M]]
[[Category: Weissella viridescens]]
[[Category: Biarrotte-Sorin, S]]
[[Category: Arthur M]]
[[Category: Maillard, A P]]
[[Category: Biarrotte-Sorin S]]
[[Category: Mayer, C]]
[[Category: Maillard AP]]
[[Category: Femx]]
[[Category: Mayer C]]
[[Category: Ligase]]
[[Category: Mutant]]
[[Category: Transferase]]
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