1y3a: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='1y3a' size='340' side='right'caption='[[1y3a]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1y3a' size='340' side='right'caption='[[1y3a]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1y3a]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3A OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Y3A FirstGlance]. <br>
<table><tr><td colspan='2'>[[1y3a]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y3A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GNAI1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1y3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y3a OCA], [http://pdbe.org/1y3a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1y3a RCSB], [http://www.ebi.ac.uk/pdbsum/1y3a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1y3a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y3a OCA], [https://pdbe.org/1y3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y3a RCSB], [https://www.ebi.ac.uk/pdbsum/1y3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y3a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 33: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Blaesius, R]]
[[Category: Blaesius R]]
[[Category: Bodor, E T]]
[[Category: Bodor ET]]
[[Category: Fredericks, Z]]
[[Category: Fredericks Z]]
[[Category: Harden, T K]]
[[Category: Harden TK]]
[[Category: Jezyk, M R]]
[[Category: Jezyk MR]]
[[Category: Johnston, C A]]
[[Category: Johnston CA]]
[[Category: Jones, M B]]
[[Category: Jones MB]]
[[Category: Ramer, J K]]
[[Category: Ramer JK]]
[[Category: Siderovski, D P]]
[[Category: Siderovski DP]]
[[Category: Sondek, J]]
[[Category: Sondek J]]
[[Category: Watts, V J]]
[[Category: Watts VJ]]
[[Category: Willard, F S]]
[[Category: Willard FS]]
[[Category: Protein-peptide complex]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/1y3a"