7a5c: Difference between revisions

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<StructureSection load='7a5c' size='340' side='right'caption='[[7a5c]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='7a5c' size='340' side='right'caption='[[7a5c]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7a5c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibch Vibch]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A5C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7A5C FirstGlance]. <br>
<table><tr><td colspan='2'>[[7a5c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A5C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=R1A:3-{[(2,2,5,5-TETRAMETHYL-1-OXO-2,5-DIHYDRO-1H-PYRROLIUM-3-YL)METHYL]DISULFANYL}-D-ALANINE'>R1A</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=R1A:3-{[(2,2,5,5-TETRAMETHYL-1-OXO-2,5-DIHYDRO-1H-PYRROLIUM-3-YL)METHYL]DISULFANYL}-D-ALANINE'>R1A</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">siaP, VC_1779 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243277 VIBCH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a5c OCA], [https://pdbe.org/7a5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a5c RCSB], [https://www.ebi.ac.uk/pdbsum/7a5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a5c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7a5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a5c OCA], [http://pdbe.org/7a5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7a5c RCSB], [http://www.ebi.ac.uk/pdbsum/7a5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7a5c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SIAP_VIBCH SIAP_VIBCH]] Part of the tripartite ATP-independent periplasmic (TRAP) transport system SiaPQM that catalyzes unidirectional Na(+)-dependent sialic acid uptake. Binds the common sialic acid N-acetylneuraminic acid (Neu5Ac) with a high affinity.<ref>PMID:22167185</ref> <ref>PMID:22556361</ref>
[https://www.uniprot.org/uniprot/SIAP_VIBCH SIAP_VIBCH] Part of the tripartite ATP-independent periplasmic (TRAP) transport system SiaPQM that catalyzes unidirectional Na(+)-dependent sialic acid uptake. Binds the common sialic acid N-acetylneuraminic acid (Neu5Ac) with a high affinity.<ref>PMID:22167185</ref> <ref>PMID:22556361</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Vibch]]
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
[[Category: Glaenzer, J]]
[[Category: Glaenzer J]]
[[Category: Hagelueken, G]]
[[Category: Hagelueken G]]
[[Category: Peter, M F]]
[[Category: Peter MF]]
[[Category: Substrate binding protein]]
[[Category: Transport protein]]
[[Category: Transporter]]
[[Category: Trap]]