7bj1: Difference between revisions

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New page: '''Unreleased structure''' The entry 7bj1 is ON HOLD Authors: Talibov, V.O., Eriksson, D., Dobritzsch, D., Danielson, U.H. Description: Crystal structure of SMYD3 with diperodon S enan...
 
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'''Unreleased structure'''


The entry 7bj1 is ON HOLD
==Crystal structure of SMYD3 with diperodon S enantiomer bound to allosteric site==
 
<StructureSection load='7bj1' size='340' side='right'caption='[[7bj1]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
Authors: Talibov, V.O., Eriksson, D., Dobritzsch, D., Danielson, U.H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7bj1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6z2r 6z2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BJ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BJ1 FirstGlance]. <br>
Description: Crystal structure of SMYD3 with diperodon S enantiomer bound to allosteric site
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=QKT:Diperodon+(S-enantiomer)'>QKT</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Talibov, V.O]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bj1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bj1 OCA], [https://pdbe.org/7bj1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bj1 RCSB], [https://www.ebi.ac.uk/pdbsum/7bj1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bj1 ProSAT]</span></td></tr>
[[Category: Dobritzsch, D]]
</table>
[[Category: Eriksson, D]]
== Function ==
[[Category: Danielson, U.H]]
[https://www.uniprot.org/uniprot/SMYD3_HUMAN SMYD3_HUMAN] Histone methyltransferase. Specifically methylates 'Lys-4' and 'Lys-5' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.<ref>PMID:15235609</ref> <ref>PMID:22419068</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cederfelt D]]
[[Category: Danielson UH]]
[[Category: Dobritzsch D]]
[[Category: Talibov VO]]
Retrieved from "https://proteopedia.org/7bj1"