1ys3: Difference between revisions

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<StructureSection load='1ys3' size='340' side='right'caption='[[1ys3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1ys3' size='340' side='right'caption='[[1ys3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ys3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1YS3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ys3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YS3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ys6|1ys6]], [[1ys7|1ys7]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ys3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys3 OCA], [https://pdbe.org/1ys3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ys3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ys3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys3 ProSAT], [https://www.topsan.org/Proteins/XMTB/1ys3 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ys3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys3 OCA], [http://pdbe.org/1ys3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ys3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ys3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys3 ProSAT], [http://www.topsan.org/Proteins/XMTB/1ys3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRRB_MYCTU PRRB_MYCTU]] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium. Probably phosphorylates PrrA.  
[https://www.uniprot.org/uniprot/PRRB_MYCTU PRRB_MYCTU] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium. Probably phosphorylates PrrA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Nowak, E]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Panjikar, S]]
[[Category: Nowak E]]
[[Category: Tucker, P]]
[[Category: Panjikar S]]
[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project]]
[[Category: Tucker P]]
[[Category: Atp-binding domain]]
[[Category: Histidine kinase]]
[[Category: Mycobacterium tuberculosis structural proteomics project]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Xmtb]]

Latest revision as of 13:38, 13 March 2024

Crystal Structure of the ATP binding domain of PrrB from Mycobacterium Tuberculosis

1ys3, resolution 1.90Å

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