1z8f: Difference between revisions

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<StructureSection load='1z8f' size='340' side='right'caption='[[1z8f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1z8f' size='340' side='right'caption='[[1z8f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z8f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8F OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1Z8F FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z8f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z8F FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1s4q|1s4q]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gmk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8f OCA], [https://pdbe.org/1z8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z8f RCSB], [https://www.ebi.ac.uk/pdbsum/1z8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8f ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1z8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z8f OCA], [http://pdbe.org/1z8f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z8f RCSB], [http://www.ebi.ac.uk/pdbsum/1z8f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z8f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KGUA_MYCTU KGUA_MYCTU]] Essential for recycling GMP and indirectly, cGMP (By similarity).[HAMAP-Rule:MF_00328]  
[https://www.uniprot.org/uniprot/KGUA_MYCTU KGUA_MYCTU] Essential for recycling GMP and indirectly, cGMP (By similarity).[HAMAP-Rule:MF_00328]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/1z8f_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/1z8f_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Guanylate kinase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chan, S]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Choi, B]]
[[Category: Chan S]]
[[Category: Perry, L J]]
[[Category: Choi B]]
[[Category: Sawaya, M R]]
[[Category: Perry LJ]]
[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project]]
[[Category: Sawaya MR]]
[[Category: Zocchi, G]]
[[Category: Zocchi G]]
[[Category: Atp:gmp-phosphotransferase]]
[[Category: Mycobacterium tuberculosis structural proteomics project]]
[[Category: PSI, Protein structure initiative]]
[[Category: Structural genomic]]
[[Category: Tbsgc]]
[[Category: Transferase]]
[[Category: Xmtb]]

Latest revision as of 08:57, 6 November 2024

Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)

1z8f, resolution 2.50Å

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