2abw: Difference between revisions
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<StructureSection load='2abw' size='340' side='right'caption='[[2abw]], [[Resolution|resolution]] 1.62Å' scene=''> | <StructureSection load='2abw' size='340' side='right'caption='[[2abw]], [[Resolution|resolution]] 1.62Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2abw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2abw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ABW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ABW FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.62Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2abw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2abw OCA], [https://pdbe.org/2abw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2abw RCSB], [https://www.ebi.ac.uk/pdbsum/2abw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2abw ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2abw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2abw OCA], [https://pdbe.org/2abw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2abw RCSB], [https://www.ebi.ac.uk/pdbsum/2abw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2abw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PDX2_PLAF7 PDX2_PLAF7] Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of Pdx1.<ref>PMID:15590634</ref> <ref>PMID:16339145</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum]] | ||
[[Category: Fitzpatrick | [[Category: Fitzpatrick TB]] | ||
[[Category: Flicker | [[Category: Flicker K]] | ||
[[Category: Gengenbacher | [[Category: Gengenbacher M]] | ||
[[Category: Kappes | [[Category: Kappes B]] | ||
[[Category: Macheroux | [[Category: Macheroux P]] | ||
[[Category: Mueller | [[Category: Mueller S]] | ||
[[Category: Raschle | [[Category: Raschle T]] | ||
[[Category: Sinning | [[Category: Sinning I]] | ||
[[Category: Tews | [[Category: Tews I]] | ||
