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[[Image:1dnm.gif|left|200px]]


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==CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)==
The line below this paragraph, containing "STRUCTURE_1dnm", creates the "Structure Box" on the page.
<StructureSection load='1dnm' size='340' side='right'caption='[[1dnm]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dnm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnm OCA], [https://pdbe.org/1dnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnm RCSB], [https://www.ebi.ac.uk/pdbsum/1dnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnm ProSAT]</span></td></tr>
{{STRUCTURE_1dnm|  PDB=1dnm  |  SCENE= }}
</table>
 
__TOC__
'''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''
</StructureSection>
 
[[Category: Large Structures]]
 
[[Category: Li BF]]
==Overview==
[[Category: Neidle S]]
The crystal structure of the dodecanucleotide d(CGCAAGCTGGCG) has been determined to a resolution of 2.5 A and refined to an R factor of 19.3% for 1710 reflections. The sequence crystallizes as a B-type double helix, with two G(anti).A(syn) base pairs. These are stabilized by three-center hydrogen bonds to pyrimidines that induce perturbations in base-pair geometry. The central AGCT region of the helix has a wide (greater than 6 A) minor groove.
[[Category: Sanderson MR]]
 
[[Category: Skelly JV]]
==About this Structure==
[[Category: Swann PF]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA].  
[[Category: Tickle IJ]]
 
[[Category: Webster GD]]
==Reference==
Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2395870 2395870]
[[Category: Li, B F.]]
[[Category: Neidle, S.]]
[[Category: Sanderson, M R.]]
[[Category: Skelly, J V.]]
[[Category: Swann, P F.]]
[[Category: Tickle, I J.]]
[[Category: Webster, G D.]]
[[Category: B-dna]]
[[Category: Double helix]]
[[Category: Mismatched]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 14:03:21 2008''

Latest revision as of 06:56, 7 February 2024

CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)

1dnm, resolution 2.50Å

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