Replication protein E1: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
   
   
The complex between BPV1 DBD and 21-bp DNA (PDB code [[1ksx]]) shows 2 DBD-DNA binding modules: a binding loop and a binding helix each interacting with a single strand. The protein-DNA interactions are hydrophilic to phosphate atoms and van der Waals hydrophobic ones<ref>PMID:11889054</ref>.
The complex between BPV1 DBD and 21-bp DNA (PDB code [[1ksx]]) shows 2 DBD-DNA binding modules: a <scene name='87/873777/Cv/2'>binding loop</scene> and a <scene name='87/873777/Cv/4'>binding helix</scene> each interacting with a single strand. The protein-DNA interactions are hydrophilic to phosphate atoms and van der Waals hydrophobic ones<ref>PMID:11889054</ref>.
</StructureSection>
</StructureSection>
==3D structures of replication protein E1==
==3D structures of replication protein E1==
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Domains: helicase 301-605; DNA-binding (DBD) 286-365
Domains: helicase 301-605; DNA-binding (DBD) 286-365


[[1r9w]] - RPE1 DBD - HPV18<br />
[[1r9w]] - HpvRPE1 DBD – Human papilloma virus 18<br />
[[1tue]] - RPE1 428-631 (mutant) + RPE2 TAD<br />
[[1tue]] - HpvRPE1 428-631 (mutant) + RPE2 TAD<br />
[[2v9p]] - RPE1 helicase domain - BPV1<br />
[[2gxa]] - DpvRPE1 helicase domain + DNA + ADP – Delta papilloma virus 4<br />
[[5a9k]] - RPE1 helicase domain - Cryo EM<br />
[[5a9k]] - BpvRPE1 helicase domain – Bovine papilloma virus - Cryo EM<br />
[[2gxa]] - RPE1 helicase domain + DNA + ADP<br />
[[2v9p]] - BpvRPE1 helicase domain <br />
[[1f08]] - RPE1 DBD<br />
[[1f08]] - BpvRPE1 DBD<br />
[[1ksx]], [[1ksy]] - RPE1 DBD + DNA<br />
[[1ksx]], [[1ksy]] - BpvRPE1 DBD + DNA<br />
[[7apd]] - BpvRPE1 helicase domain + DNA – Cryo EM<br />
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]