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==THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA==
==THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA==
<StructureSection load='1agg' size='340' side='right'caption='[[1agg]], [[NMR_Ensembles_of_Models | 24 NMR models]]' scene=''>
<StructureSection load='1agg' size='340' side='right'caption='[[1agg]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1agg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agelenopsis_aperta Agelenopsis aperta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AGG FirstGlance]. <br>
<table><tr><td colspan='2'>[[1agg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agelenopsis_aperta Agelenopsis aperta]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AGG FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1agg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1agg OCA], [https://pdbe.org/1agg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1agg RCSB], [https://www.ebi.ac.uk/pdbsum/1agg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1agg ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1agg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1agg OCA], [https://pdbe.org/1agg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1agg RCSB], [https://www.ebi.ac.uk/pdbsum/1agg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1agg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TOG4B_AGEAP TOG4B_AGEAP]] Antagonist of voltage-gated Cav2.1/CACNA1A (P-type) calcium channels. Paralyzes insect by blocking neuromuscular transmission.<ref>PMID:8232218</ref>
[https://www.uniprot.org/uniprot/TX23B_AGEAP TX23B_AGEAP] Antagonist of voltage-gated Cav2.1/CACNA1A (P-type) calcium channels. Paralyzes insect by blocking neuromuscular transmission.<ref>PMID:8232218</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Agelenopsis aperta]]
[[Category: Agelenopsis aperta]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Adams, M E]]
[[Category: Adams ME]]
[[Category: Reily, M D]]
[[Category: Reily MD]]
[[Category: Thanabal, V]]
[[Category: Thanabal V]]
[[Category: Neurotoxin]]
[[Category: P-type calcium channel antagonist]]

Latest revision as of 05:24, 5 June 2024

THE SOLUTION STRUCTURE OF OMEGA-AGA-IVB, A P-TYPE CALCIUM CHANNEL ANTAGONIST FROM THE VENOM OF AGELENOPSIS APERTA

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