2c7s: Difference between revisions
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<StructureSection load='2c7s' size='340' side='right'caption='[[2c7s]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='2c7s' size='340' side='right'caption='[[2c7s]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c7s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2c7s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7S FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7s OCA], [https://pdbe.org/2c7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7s RCSB], [https://www.ebi.ac.uk/pdbsum/2c7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7s ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7s OCA], [https://pdbe.org/2c7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7s RCSB], [https://www.ebi.ac.uk/pdbsum/2c7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PTPRK_HUMAN PTPRK_HUMAN] Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa.<ref>PMID:19836242</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith C]] | |||
[[Category: Arrowsmith | [[Category: Barr A]] | ||
[[Category: Barr | [[Category: Burgess N]] | ||
[[Category: Burgess | [[Category: Das S]] | ||
[[Category: Das | [[Category: Debreczeni JE]] | ||
[[Category: Debreczeni | [[Category: Edwards A]] | ||
[[Category: Eswaran J]] | |||
[[Category: Edwards | [[Category: Gileadi O]] | ||
[[Category: Eswaran | [[Category: Knapp S]] | ||
[[Category: Gileadi | [[Category: Longman E]] | ||
[[Category: Knapp | [[Category: Sundstron M]] | ||
[[Category: Longman | [[Category: Ugochukwu E]] | ||
[[Category: Sundstron | [[Category: Weigelt J]] | ||
[[Category: Ugochukwu | [[Category: Von Delft F]] | ||
[[Category: Weigelt | |||
[[Category: | |||
