7de3: Difference between revisions

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'''Unreleased structure'''


The entry 7de3 is ON HOLD  until Paper Publication
==Human adenylate kinase 1 (hAK1) mutant-R128W==
<StructureSection load='7de3' size='340' side='right'caption='[[7de3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7de3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DE3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.197&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7de3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7de3 OCA], [https://pdbe.org/7de3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7de3 RCSB], [https://www.ebi.ac.uk/pdbsum/7de3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7de3 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KAD1_HUMAN KAD1_HUMAN] Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD) [MIM:[https://omim.org/entry/612631 612631].<ref>PMID:2542324</ref> <ref>PMID:9432020</ref> <ref>PMID:12649162</ref>
== Function ==
[https://www.uniprot.org/uniprot/KAD1_HUMAN KAD1_HUMAN] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.


Authors: Lin, W.
==See Also==
 
*[[Adenylate kinase 3D structures|Adenylate kinase 3D structures]]
Description: Human adenylate kinase 1 (hAK1) mutant-R128W
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Lin, W]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lin W]]
Retrieved from "https://proteopedia.org/7de3"