2c6x: Difference between revisions

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New page: left|200px<br /> <applet load="2c6x" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c6x, resolution 3.40Å" /> '''STRUCTURE OF BACILL...
 
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[[Image:2c6x.gif|left|200px]]<br />
<applet load="2c6x" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2c6x, resolution 3.40&Aring;" />
'''STRUCTURE OF BACILLUS SUBTILIS CITRATE SYNTHASE'''<br />


==About this Structure==
==Structure of Bacillus subtilis citrate synthase==
2C6X is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]] with COZ and CIT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.1 2.3.3.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C6X OCA]].
<StructureSection load='2c6x' size='340' side='right'caption='[[2c6x]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2c6x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C6X FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=COZ:COENZYME+A'>COZ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c6x OCA], [https://pdbe.org/2c6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c6x RCSB], [https://www.ebi.ac.uk/pdbsum/2c6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c6x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CISY_BACSU CISY_BACSU] Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c6/2c6x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c6x ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Crennell, S.J.]]
[[Category: Crennell SJ]]
[[Category: Danson, M.J.]]
[[Category: Danson MJ]]
[[Category: Hough, D.W.]]
[[Category: Hough DW]]
[[Category: Vogl, C.]]
[[Category: Vogl C]]
[[Category: CIT]]
[[Category: COZ]]
[[Category: allosteric enzyme]]
[[Category: bacillus subtilis]]
[[Category: citrate synthase]]
[[Category: enzyme thermostability]]
[[Category: transferase]]
[[Category: tricarboxylic acid cycle]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:58:01 2007''

Latest revision as of 06:09, 1 October 2025

Structure of Bacillus subtilis citrate synthase

2c6x, resolution 3.40Å

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