7nnz: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 7nnz is ~~ON HOLD until Paper Publication~~

==Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.==

== Structural highlights ==

<table><tr><td colspan='2'>[[7nnz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NNZ OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7NNZ FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PTZ:5-methyl-4-phenyl-1,3-thiazol-2-amine'>PTZ</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7nnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nnz OCA], [https://pdbe.org/7nnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nnz RCSB], [https://www.ebi.ac.uk/pdbsum/7nnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nnz ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/OTC_MYCTU OTC_MYCTU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]

~~Authors: Mendes, V., Gupta, P., Burgess, A., Sebastian-Perez, V., Cattermole, E., Meghir, C., Blundell, T.L.~~

==See Also==

*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]

~~Description~~: ~~Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.~~

__TOC__

[[Category: ~~Unreleased Structures~~]]

</StructureSection>

[[Category: ~~Sebastian-Perez, V~~]]

[[Category: Large Structures]]

[[Category: ~~Meghir, C~~]]

[[Category: Mycobacterium tuberculosis H37Rv]]

[[Category: ~~Blundell, T.L~~]]

[[Category: Blundell TL]]

[[Category: ~~Mendes, V~~]]

[[Category: Burgess A]]

[[Category: ~~Burgess, A~~]]

[[Category: Cattermole E]]

[[Category: ~~Cattermole, E~~]]

[[Category: Gupta P]]

[[Category: ~~Gupta, P~~]]

[[Category: Meghir C]]

[[Category: Mendes V]]

[[Category: Sebastian-Perez V]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7nnz is ON HOLD  until Paper Publication
+==Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.==
+<StructureSection load='7nnz' size='340' side='right'caption='[[7nnz]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7nnz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NNZ FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PTZ:5-methyl-4-phenyl-1,3-thiazol-2-amine'>PTZ</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nnz OCA], [https://pdbe.org/7nnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nnz RCSB], [https://www.ebi.ac.uk/pdbsum/7nnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nnz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OTC_MYCTU OTC_MYCTU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]
-Authors: Mendes, V., Gupta, P., Burgess, A., Sebastian-Perez, V., Cattermole, E., Meghir, C., Blundell, T.L.
+==See Also==
+*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
-Description: Crystal structure of Mycobacterium tuberculosis ArgF in complex with 5-methyl-4-phenylthiazol-2-amine.
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Sebastian-Perez, V]]
+[[Category: Large Structures]]
-[[Category: Meghir, C]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
-[[Category: Blundell, T.L]]
+[[Category: Blundell TL]]
-[[Category: Mendes, V]]
+[[Category: Burgess A]]
-[[Category: Burgess, A]]
+[[Category: Cattermole E]]
-[[Category: Cattermole, E]]
+[[Category: Gupta P]]
-[[Category: Gupta, P]]
+[[Category: Meghir C]]
+[[Category: Mendes V]]
+[[Category: Sebastian-Perez V]]