7np0: Difference between revisions

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New page: '''Unreleased structure''' The entry 7np0 is ON HOLD until Paper Publication Authors: Mendes, V., Gupta, P., Burgess, A., Sebastian-Perez, V., Cattermole, E., Meghir, C., Blundell, T.L....
 
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'''Unreleased structure'''


The entry 7np0 is ON HOLD  until Paper Publication
==Crystal structure of Mycobacterium tuberculosis ArgF in complex with (4-nitrophenyl)boronic acid.==
<StructureSection load='7np0' size='340' side='right'caption='[[7np0]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7np0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NP0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UKH:p-nitrophenylboronic+acid'>UKH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7np0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7np0 OCA], [https://pdbe.org/7np0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7np0 RCSB], [https://www.ebi.ac.uk/pdbsum/7np0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7np0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OTC_MYCTU OTC_MYCTU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109]


Authors: Mendes, V., Gupta, P., Burgess, A., Sebastian-Perez, V., Cattermole, E., Meghir, C., Blundell, T.L.
==See Also==
 
*[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]]
Description: Crystal structure of Mycobacterium tuberculosis ArgF in complex with (4-nitrophenyl)boronic acid.
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Sebastian-Perez, V]]
[[Category: Large Structures]]
[[Category: Meghir, C]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Blundell, T.L]]
[[Category: Blundell TL]]
[[Category: Mendes, V]]
[[Category: Burgess A]]
[[Category: Burgess, A]]
[[Category: Cattermole E]]
[[Category: Cattermole, E]]
[[Category: Gupta P]]
[[Category: Gupta, P]]
[[Category: Meghir C]]
[[Category: Mendes V]]
[[Category: Sebastian-Perez V]]
Retrieved from "https://proteopedia.org/7np0"