2gpu: Difference between revisions

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<StructureSection load='2gpu' size='340' side='right'caption='[[2gpu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2gpu' size='340' side='right'caption='[[2gpu]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GPU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gp7|2gp7]], [[2gpo|2gpo]], [[2gpp|2gpp]], [[2gpv|2gpv]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ESRRG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gpu OCA], [https://pdbe.org/2gpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gpu RCSB], [https://www.ebi.ac.uk/pdbsum/2gpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gpu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gpu OCA], [https://pdbe.org/2gpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gpu RCSB], [https://www.ebi.ac.uk/pdbsum/2gpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gpu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN]] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>
[https://www.uniprot.org/uniprot/ERR3_HUMAN ERR3_HUMAN] Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).<ref>PMID:19067653</ref> <ref>PMID:18063693</ref> <ref>PMID:11864604</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Consler, T G]]
[[Category: Consler TG]]
[[Category: Lambert, M H]]
[[Category: Lambert MH]]
[[Category: McKee, D D]]
[[Category: McKee DD]]
[[Category: Miller, A B]]
[[Category: Miller AB]]
[[Category: Nolte, R T]]
[[Category: Nolte RT]]
[[Category: Osband-Miller, L A]]
[[Category: Osband-Miller LA]]
[[Category: Wang, L]]
[[Category: Wang L]]
[[Category: Willson, T M]]
[[Category: Willson TM]]
[[Category: Zuercher, W J]]
[[Category: Zuercher WJ]]
[[Category: Err]]
[[Category: Errg]]
[[Category: Esrrg]]
[[Category: Estrogen related receptor]]
[[Category: Nuclear receptor]]
[[Category: Steroid receptor]]
[[Category: Transcription]]
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