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==SOLUTION STRUCTURE OF CONOTOXIN TVIIA FROM CONUS TULIPA==
==SOLUTION STRUCTURE OF CONOTOXIN TVIIA FROM CONUS TULIPA==
<StructureSection load='1eyo' size='340' side='right'caption='[[1eyo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1eyo' size='340' side='right'caption='[[1eyo]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1eyo]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EYO FirstGlance]. <br>
<table><tr><td colspan='2'>[[1eyo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_tulipa Conus tulipa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EYO FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eyo OCA], [https://pdbe.org/1eyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eyo RCSB], [https://www.ebi.ac.uk/pdbsum/1eyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eyo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eyo OCA], [https://pdbe.org/1eyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eyo RCSB], [https://www.ebi.ac.uk/pdbsum/1eyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eyo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/C7A_CONTU C7A_CONTU]] By structural similarity with conotoxin GS, may inhibit the sodium channel (Nav). No effect was observed upon intracranial injections into mice and intraperitoneal injections into goldfish (25 ug).  
[https://www.uniprot.org/uniprot/U7A_CONTU U7A_CONTU] By structural similarity with conotoxin GS, may inhibit the sodium channel (Nav). No effect was observed upon intracranial injections into mice and intraperitoneal injections into goldfish (25 ug).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Conus tulipa]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Alewood, P F]]
[[Category: Alewood PF]]
[[Category: Craik, D J]]
[[Category: Craik DJ]]
[[Category: Hill, J M]]
[[Category: Hill JM]]
[[Category: Cystine knot motif]]
[[Category: Toxin]]
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