6y4n: Difference between revisions
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==== | ==Structure of Tubulin Tyrosine Ligase in Complex with Tb116== | ||
<StructureSection load='6y4n' size='340' side='right'caption='[[6y4n]]' scene=''> | <StructureSection load='6y4n' size='340' side='right'caption='[[6y4n]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[6y4n]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y4N FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y4n OCA], [https://pdbe.org/6y4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y4n RCSB], [https://www.ebi.ac.uk/pdbsum/6y4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y4n ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.852Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=O9B:(2~{R})-1-methylpiperidine-2-carboxylic+acid'>O9B</scene>, <scene name='pdbligand=O9K:[(1~{R},3~{R})-1-(4-methanoyl-1,3-thiazol-2-yl)-4-methyl-3-(methylamino)pentyl]+ethanoate'>O9K</scene>, <scene name='pdbligand=O9N:methyl+(2~{S},4~{S})-2,4-bis(azanyl)-5-phenyl-pentanoate'>O9N</scene>, <scene name='pdbligand=P6S:benzyl+hydrogen+carbonate'>P6S</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y4n OCA], [https://pdbe.org/6y4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y4n RCSB], [https://www.ebi.ac.uk/pdbsum/6y4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y4n ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
==See Also== | |||
*[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | |||
*[[Tubulin 3D Structures|Tubulin 3D Structures]] | |||
*[[Tubulin tyrosine ligase 3D structures|Tubulin tyrosine ligase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: Sus scrofa]] | |||
[[Category: Gavrilyuk J]] | |||
[[Category: Nicolaou KC]] | |||
[[Category: Nocek B]] | |||
[[Category: Rigol S]] | |||
[[Category: Stoll V]] | |||
Latest revision as of 06:09, 19 June 2024
Structure of Tubulin Tyrosine Ligase in Complex with Tb116
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