1gkn: Difference between revisions

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==Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)==
==Structure Determination and Rational Mutagenesis reveal binding surface of immune adherence receptor, CR1 (CD35)==
<StructureSection load='1gkn' size='340' side='right'caption='[[1gkn]], [[NMR_Ensembles_of_Models | 24 NMR models]]' scene=''>
<StructureSection load='1gkn' size='340' side='right'caption='[[1gkn]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1gkn]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GKN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1gkn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GKN FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gkg|1gkg]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 24 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gkn OCA], [https://pdbe.org/1gkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gkn RCSB], [https://www.ebi.ac.uk/pdbsum/1gkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gkn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gkn OCA], [https://pdbe.org/1gkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gkn RCSB], [https://www.ebi.ac.uk/pdbsum/1gkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gkn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CR1_HUMAN CR1_HUMAN] Mediates cellular binding of particles and immune complexes that have activated complement.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gkn_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gkn_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Atkinson, J P]]
[[Category: Atkinson JP]]
[[Category: Barlow, P N]]
[[Category: Barlow PN]]
[[Category: Bromek, K]]
[[Category: Bromek K]]
[[Category: Hauhart, R E]]
[[Category: Hauhart RE]]
[[Category: Krych-Goldberg, M]]
[[Category: Krych-Goldberg M]]
[[Category: Mallin, R L]]
[[Category: Mallin RL]]
[[Category: Smith, B O]]
[[Category: Smith BO]]
[[Category: Uhrin, D]]
[[Category: Uhrin D]]
[[Category: Wang, X]]
[[Category: Wang X]]
[[Category: Complement]]
[[Category: Module]]
[[Category: Scr]]
Retrieved from "https://proteopedia.org/1gkn"